By Victor Leung, Dana Nyholt-Bailey, IQMH Endocrinology and Immunology Scientific Committee and Staff
Recent years have seen a significant increase in the number of cases of biotin interference with streptavidin-biotin (SB)-based immunoassays reported in the literature. Biotin interference with laboratory tests, specifically SB-based immunoassays, is potentially dangerous, as it may cause spurious test results leading to misdiagnosis and patient mismanagement.
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