The IQMH Centre for Proficiency Testing has published a document for participants in the Transfusion Medicine proficiency testing program. Review – Crossmatching, developed by members of the IQMH Transfusion Medicine Scientific Committee, summarizes the current scientific literature regarding crossmatching. The document will be reviewed and updated periodically for continued relevance.
One of the ultimate goals of the transfusion service (TS) is to provide the safest and most appropriate compatible red blood cells (RBC) for transfusion. Testing for compatibility commences with ABO/Rh determination and antibody screening. Investigation and identification of unexpected antibodies must be performed by the originating TS or may be forwarded to a reference laboratory. The final step in providing compatible RBCs is the crossmatch procedure.
Review – Crossmatching includes a discussion of the following topics:
Each TS should have detailed instructions on how to perform compatibility testing and on which method of crossmatch to employ for various clinical situations. While the recipient’s blood testing record will be the main factor in determining the most appropriate crossmatch method to use, the testing volume and expertise of the laboratory should also be considered when selecting crossmatching methods.
IQMH Transfusion Medicine program participants can login to QView.ca with their username and password to download the document: Review – Crossmatching.
For more information on how your facility can become a participant in the IQMH Transfusion Medicine Proficiency Testing program:
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